Binimetinib | CAS 606143-89-9 API Manufacturer & Supplier in China

Product Overview

Binimetinib (CAS 606143-89-9) is a potent and highly selective small-molecule inhibitor of mitogen-activated protein kinase kinase 1 (MEK1) and kinase 2 (MEK2). As a critical non-ATP-competitive inhibitor within the MAPK/ERK pathway, it plays a vital role in biochemical research focusing on the regulation of cell proliferation and survival in various hyperproliferative models. Within the Pharmaceutical APIs and oncology research sectors, Binimetinib is recognized for its technical capacity to suppress downstream signaling molecules, thereby inhibiting the growth of cell lines driven by specific genetic mutations such as BRAF or NRAS. As a leading manufacturer of Binimetinib CAS 606143-89-9 based in China, Conscientia Industrial utilizes high-precision multi-step organic synthesis and advanced purification technologies to ensure the highest structural integrity and a consistent crystalline form. Our product maintains a rigorous purity profile designed to meet the technical requirements of global research laboratories and industrial scale-up projects. We focus on batch-to-batch reproducibility to ensure that every shipment delivers the same chemical performance required for sensitive analytical applications and formulation development.

Technical Specifications

• Product Name: Binimetinib

• CAS Number: 606143-89-9

• Category: Pharmaceutical APIs

• Quality Standard: In-House

• Molecular Formula: C17H15BrF2N4O3

• Molecular Weight: 441.23

• Appearance: White to off-white crystalline powder

• Solubility: Soluble in DMSO and Methanol; practically insoluble in water

• Purity (HPLC): ≥98.0%

• Loss on Drying: ≤1.0%

• Residue on Ignition: ≤0.1%

• Heavy Metals: ≤20ppm

• Brand: Conscientia Industrial

• Country of Origin: China

• Availability: In Stock

• Pricing: Competitive price based on order quantity

• Currency: USD

• Molecular Structure:

Why Partner with Conscientia Industrial

• Technical Quality Control: Our manufacturing process follows rigorous analytical protocols to ensure high-grade batch-to-batch consistency for Binimetinib CAS 606143-89-9.

• Advanced Analytical Verification: Every batch is validated through HPLC and Proton NMR to confirm chemical identity and minimize the presence of related substances or process impurities.

• Full Technical Documentation: We provide comprehensive support, including the Certificate of Analysis (COA), MSDS, and Method of Analysis (MOA) for Binimetinib CAS 606143-89-9.

• Scalable Production Capacity: Our China facility is equipped to support projects ranging from milligram-level laboratory research to large-scale bulk industrial supply with optimized reaction yields.

• Direct Source Advantage: As a primary manufacturer, we provide Binimetinib CAS 606143-89-9 with efficient lead times and direct factory technical support to address any specific formulation or research inquiries.

• Reliable Supply Chain: We maintain a robust procurement system for raw materials to guarantee long-term availability and price stability for our global partners.

Packaging & Storage

• Standard Packaging: 100g/aluminum foil bag, 1kg/aluminum foil bag, or 25kg/fiber drum with dual PE protection.

• Storage Conditions: Store in a tightly closed container in a cool, dry environment. Protected from light and moisture.

• Shelf Life: 24 months when stored under the recommended conditions.

• Safety Handling: This material is a technical-grade chemical intended for industrial production and laboratory research use only. It should be handled by trained professionals using appropriate personal protective equipment.

Our logistics team ensures secure distribution of Binimetinib CAS 606143-89-9 via global courier, air freight, and sea freight with full tracking capabilities.

Request a Quote & COA for Binimetinib CAS 606143-89-9 Today.