Product Overview
4-(6-((4-(Trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenol (CAS 2489876-34-6), also known as GMB-475, is a functional ligand designed for proteolysis targeting chimera (PROTAC) development. In target protein degradation and oncology research, this compound is utilized as an allosteric BCR-ABL1 targeting unit to recruit the Von Hippel-Lindau (VHL) E3 ubiquitin ligase, inducing ubiquitination and degradation of BCR-ABL1 protein. Conscientia Industrial produces 4-(6-((4-(Trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenol through multi-step organic synthesis and crystallization techniques to ensure consistent product purity.
Technical Specifications
| Product Name: | 4-(6-((4-(Trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenol |
| CAS Number: | 2489876-34-6 |
| Category: | Fine Chemicals |
| Molecular Formula: | C17H12F3N3O2 |
| Molecular Weight: | 347.29 |
| Quality Standard: | In-House Specification |
| Appearance: | White to pale yellow solid |
| Purity (HPLC): | ≥98.0% |
| Manufacturer: | Conscientia Industrial |
| Brand: | Conscientia Industrial |
| Country of Origin: | China |
Why Choose Conscientia Industrial
- Quality Assurance: Every batch of 4-(6-((4-(Trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenol is analyzed by HPLC and NMR to confirm identity and chemical purity.
- Documentation: Certificate of Analysis (COA), Safety Data Sheet (SDS), and Method of Analysis (MOA) are provided.
- Production Capacity: Synthesis infrastructure supports flexible orders from gram-scale research quantities to bulk commercial manufacturing.
- Direct Supply: Direct factory manufacturing ensures stable inventory, competitive pricing, and technical support.
Packaging & Storage
- Packaging: Available in 1g, 5g, 10g, 50g, 100g, 500g, 1kg in bottles or aluminium foil bags. Customized packaging and private labeling services are available upon request.
- Storage Condition: Store sealed at 2-8°C or -20°C in a dry and dark place.
- Shelf Life: 24 months when properly stored under recommended conditions.
Shipping & Quotes
- Conscientia Industrial provides worldwide logistics solutions for 4-(6-((4-(Trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenol (CAS 2489876-34-6), including international courier service, air freight, and sea freight. A complete set of shipping documents is provided to support international import and export requirements.
- Contact us today for the latest quotation, COA, SDS, and technical documentation.
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