Boc-Gly-Gly-Phe-Gly-PAB-PNP CAS 251459-29-7

Product Overview

Boc-Gly-Gly-Phe-Gly-PAB-PNP (CAS 251459-29-7) is a sophisticated tetrapeptide linker intermediate specifically designed for the development of Antibody-Drug Conjugates (ADCs). This complex molecule incorporates a Boc-protected N-terminus and a p-nitrophenyl (PNP) carbonate activated C-terminus, separated by a cathepsin B-cleavable tetrapeptide sequence and a para-aminobenzyl (PAB) self-immolative spacer. Within the Peptides and bioconjugation research sectors, it is highly valued for its technical role in ensuring precise drug release mechanisms and enhancing the therapeutic index of targeted biologics in laboratory models. As a professitional manufacturer of Boc-Gly-Gly-Phe-Gly-PAB-PNP CAS 251459-29-7 based in China, Conscientia Industrial utilizes high-precision solid-phase peptide synthesis (SPPS) and advanced chromatographic purification to ensure the highest structural integrity and chemical stability. Our product maintains a strict purity profile to meet global technical requirements for batch-to-batch consistency in advanced medicinal chemistry and oncological research.

Technical Specifications

• Product Name: Boc-Gly-Gly-Phe-Gly-PAB-PNP
• Synonyms: Boc-GGFG-PAB-PNP
• CAS Number: 251459-29-7
• Category: Peptides
• Quality Standard: In-House
• Purity (HPLC): ≥98.0%
• Molecular Formula: C34H38N6O11
• Molecular Weight: 706.70
• Appearance: White to light yellow powder
• Loss on Drying: ≤1.0%
• Residue on Ignition: ≤0.2%
• Solubility: Soluble in DMF, DMSO
• Brand: Conscientia Industrial
• Country of Origin: China

Why Choose Conscientia Industrial

• Technical Quality Control: Our manufacturing process follows rigorous analytical protocols to ensure high-grade batch-to-batch consistency for Boc-Gly-Gly-Phe-Gly-PAB-PNP CAS 251459-29-7.
• Advanced Analytical Verification: Every batch is validated through HPLC and Proton NMR to confirm chemical identity, ensuring that the peptide sequence and the activated carbonate group remain intact without degradation.
• Full Technical Documentation: We provide comprehensive support, including Certificate of Analysis (COA), MSDS, and Method of Analysis (MOA) for Boc-Gly-Gly-Phe-Gly-PAB-PNP CAS 251459-29-7 to facilitate seamless regulatory compliance.
• Scalable Production Capacity: Our China facility is equipped to support projects ranging from milligram-scale laboratory research to large-scale bulk industrial supply for clinical-stage development.
• Direct Source Advantage: As a primary manufacturer, we provide Boc-Gly-Gly-Phe-Gly-PAB-PNP CAS 251459-29-7 with efficient lead times and direct factory technical support to address complex conjugation challenges.

Packaging & Storage

• Standard Packaging: 1mg, 10mg, 100mg, 1g, 10g, 100g in amber glass bottles or aluminum foil bags with moisture-proof desiccants.
• Storage Conditions: Store in a tightly closed container at -20°C. This product is highly sensitive to moisture and light; keep under argon or nitrogen for optimal stability.
• Shelf Life: 24 months when stored under recommended conditions in the original unopened packaging.
• Safety Handling: This material is a technical-grade chemical intended for industrial production and laboratory research use only. It should be handled by trained personnel familiar with reactive peptide intermediates.

Our logistics team ensures secure distribution of Boc-Gly-Gly-Phe-Gly-PAB-PNP CAS 251459-29-7 via global courier, and air freight.

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