CAS 2212022-56-3 | Orforglipron intermediate Manufacturer & Supplier

Product Overview

CAS 2212022-56-3, (S)-1-(4-Fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)-1H-imidazol-2(3H)-one is a sophisticated organic building block recognized primarily as a critical advanced intermediate for the synthesis of Orforglipron. Orforglipron is a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist currently garnering significant attention in clinical research for the management of type 2 diabetes and obesity. Within the Pharmaceutical Intermediates and medicinal chemistry sectors, this specific molecule is indispensable due to its complex heterocyclic architecture, which includes indazole, imidazole, and tetrahydro-pyrazolo-pyridine moieties. The precise (S)-enantiomeric configuration is essential for the biological activity of the final API, as it ensures the correct spatial orientation for receptor binding.

As a leading manufacturer of (S)-1-(4-Fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)-1H-imidazol-2(3H)-one CAS 2212022-56-3 based in China, Conscientia Industrial employs advanced asymmetric synthesis and high-resolution purification technologies. Our production process involves multiple intricate steps, including controlled ring closures and stereoselective catalysis, to ensure that the final crystalline powder meets the most stringent pharmaceutical research standards. Given the complexity of this Orforglipron intermediate, our technical team maintains rigorous oversight of the synthesis pathway to minimize the presence of isomeric impurities and related substances. This commitment to quality ensures that our clients receive a consistent material that optimizes the yield and efficiency of their subsequent downstream synthesis.

Technical Specifications

• Product Name: (S)-1-(4-Fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)-1H-imidazol-2(3H)-one

• CAS Number: 2212022-56-3

• Category: Pharmaceutical Intermediates

• Quality Standard: In-House Specification

• Purity (HPLC): ≥98.0%

• Chiral Purity (ee): ≥99%

• Molecular Formula: C26H25F2N7O

• Molecular Weight: 489.52

• Appearance: White to light yellow crystalline powder

• Loss on Drying: ≤1.0%

• Residue on Ignition: ≤0.2%

• Application: Orforglipron intermediate

• Brand: Conscientia Industrial

• Country of Origin: China

• Availability: In Stock

• Pricing: Competitive price based on order quantity

• Currency: USD

• Molecular Structure:

Why Partner with Conscientia Industrial

• Technical Quality Control: Our manufacturing process follows rigorous analytical protocols to ensure high-grade batch-to-batch consistency for (S)-1-(4-Fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)-1H-imidazol-2(3H)-one CAS 2212022-56-3.

• Advanced Analytical Verification: Every batch is validated through HPLC, LC-MS, and Chiral HPLC to confirm chemical identity and ensure the highest possible enantiomeric excess.

• Full Technical Documentation: We provide comprehensive support, including Certificate of Analysis (COA), MSDS, and Method of Analysis (MOA) specifically for (S)-1-(4-Fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)-1H-imidazol-2(3H)-one CAS 2212022-56-3.

• Scalable Production Capacity: Our China facility is equipped to support projects ranging from small-scale laboratory investigation to large-scale bulk industrial supply for drug development programs.

• Direct Source Advantage: As a primary manufacturer, we provide this Orforglipron intermediate with efficient lead times, technical transparency, and direct factory-to-lab support.

Packaging & Storage

• Standard Packaging: 100g, 500g, 1kg per bottle or vacuum-sealed aluminum foil bag; 25kg/fiber drum for bulk orders.

• Storage Conditions: Store in a tightly closed container in a cool, dry, and well-ventilated area. Recommended storage is 2-8°C or below for long-term stability. Protected from light and oxidative environments.

• Shelf Life: 24 months when stored under the specified conditions.

• Safety Handling: This material is a technical-grade chemical intermediate intended for industrial production and laboratory research use only. Appropriate personal protective equipment (PPE) should be worn during handling.

Our logistics team ensures secure distribution of (S)-1-(4-Fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)-1H-imidazol-2(3H)-one CAS 2212022-56-3 via global courier, air freight, and sea freight, maintaining all necessary regulatory compliance.

Request a Quote & COA for (S)-1-(4-Fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)-1H-imidazol-2(3H)-one CAS 2212022-56-3 Today.