CAS 2212021-83-3 | Orforglipron intermediate Manufacturer & Supplier

Product Overview

CAS 2212021-83-3, 1-((1S,2S)-1-cyano-2-methylcyclopropyl)-5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide is a highly sophisticated organic compound functioning as a vital Orforglipron intermediate. Orforglipron is a non-peptide, small molecule glucagon-like peptide-1 (GLP-1) receptor agonist currently in advanced clinical development for the management of type 2 diabetes and obesity. Within the Pharmaceutical Intermediates and fine chemical sectors, this specific intermediate is critical for constructing the core molecular architecture of the final API, ensuring the necessary stereochemical configuration for biological activity. As a leading manufacturer of 1-((1S,2S)-1-cyano-2-methylcyclopropyl)-5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide CAS 2212021-83-3 based in China, Conscientia Industrial utilizes complex multi-step organic synthesis and chiral resolution techniques to maintain the strict isomeric purity required for such high-value drug precursors. Our manufacturing process focuses on the precise installation of the cyano-methylcyclopropyl moiety and the dimethyltetrahydro-pyran group, ensuring that each batch meets the rigorous internal standards for chemical integrity and process efficiency in downstream API production. Our product supports global pharmaceutical companies and research institutions in developing next-generation metabolic disease treatments.

Technical Specifications

• Product Name: 1-((1S,2S)-1-cyano-2-methylcyclopropyl)-5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide

• CAS Number: 2212021-83-3

• Category: Pharmaceutical Intermediates

• Quality Standard: In-House Specification

• Purity (HPLC): ≥98.0%

• Molecular Formula: C22H25N3O5

• Molecular Weight: 411.46

• Appearance: White to light yellow powder

• Loss on Drying: ≤1.0%

• Residue on Ignition: ≤0.1%

• Single Impurity: ≤1.0%

• Application: Orforglipron intermediate

• Brand: Conscientia Industrial

• Country of Origin: China

• Availability: In Stock

• Pricing: Competitive price based on order quantity

• Currency: USD

• Molecular Structure:

Why Partner with Conscientia Industrial

• Technical Quality Control: Our manufacturing process follows rigorous analytical protocols to ensure high-grade batch-to-batch consistency for 1-((1S,2S)-1-cyano-2-methylcyclopropyl)-5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide CAS 2212021-83-3.

• Advanced Analytical Verification: Every batch is validated through HPLC, LC-MS, and H-NMR to confirm chemical identity, stereochemical purity, and the absence of residual metallic catalysts.

• Full Technical Documentation: We provide comprehensive support, including Certificate of Analysis (COA), MSDS, and Method of Analysis (MOA) for 1-((1S,2S)-1-cyano-2-methylcyclopropyl)-5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide CAS 2212021-83-3.

• Scalable Production Capacity: Our China facility is equipped with specialized reactors and purification systems to support projects ranging from kilogram-scale clinical trial support to large-scale industrial manufacturing.

• Direct Source Advantage: As a primary manufacturer, we provide 1-((1S,2S)-1-cyano-2-methylcyclopropyl)-5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide CAS 2212021-83-3 with efficient lead times and direct factory technical support.

Packaging & Storage

• Standard Packaging: 1kg/bag, 5kg/bag, or 25kg/fiber drum with triple-layer moisture-proof protection.

• Storage Conditions: Store in a tightly closed container in a cool, dark, and well-ventilated area. Recommended storage temperature is 2-8°C or as specified for long-term stability.

• Shelf Life: 24 months when stored under the recommended conditions.

• Safety Handling: This material is a technical-grade chemical intermediate intended for industrial production and laboratory research use only. Appropriate personal protective equipment (PPE) should be worn during handling.

Our logistics team ensures secure distribution of 1-((1S,2S)-1-cyano-2-methylcyclopropyl)-5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide CAS 2212021-83-3 via global courier, air freight, and sea freight.

Request a Quote & COA for 1-((1S,2S)-1-cyano-2-methylcyclopropyl)-5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-N-phenyl-1H-indole-2-carboxamide CAS 2212021-83-3 Today.