CAS 2212021-82-2 | Orforglipron intermediate Manufacturer & Supplier

Product Overview

CAS 2212021-82-2, 5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-N-phenyl-1H-indole-2-carboxamide is a highly sophisticated organic compound that functions as a pivotal late-stage intermediate in the synthesis of Orforglipron, a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist. Within the Pharmaceutical Intermediates and medicinal chemistry sectors, this specific molecule is indispensable due to its complex chiral configuration, featuring a unique indole backbone coupled with an oxadiazolone moiety and a tetrahydropyran substituent. As a leading manufacturer of 5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-N-phenyl-1H-indole-2-carboxamide CAS 2212021-82-2 based in China, Conscientia Industrial employs state-of-the-art asymmetric synthesis and high-resolution chromatographic purification techniques to ensure the absolute stereochemical integrity of the (S,1S,2S) configuration. Our production process is meticulously monitored to control related impurities, ensuring that the crystalline structure and chemical potency meet the stringent requirements of pharmaceutical manufacturers focused on metabolic disease therapeutics. This intermediate represents the cutting edge of small-molecule GLP-1 research, providing a scalable pathway for high-efficiency drug development.

Technical Specifications

• Product Name: 5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-N-phenyl-1H-indole-2-carboxamide

• CAS Number: 2212021-82-2

• Category: Pharmaceutical Intermediates

• Quality Standard: In-House Specification

• Purity (HPLC): ≥99.0%

• Molecular Formula: C29H32N4O4

• Molecular Weight: 500.59

• Loss on Drying: ≤1.0%

• Residue on Ignition: ≤0.1%

• Single Impurity: ≤0.5%

• Application: Orforglipron intermediate

• Brand: Conscientia Industrial

• Country of Origin: China

• Availability: In Stock

• Pricing: Competitive price based on order quantity

• Currency: USD

• Molecular Structure:

Why Partner with Conscientia Industrial

• Technical Quality Control: Our manufacturing process follows rigorous analytical protocols to ensure high-grade batch-to-batch consistency for 5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-N-phenyl-1H-indole-2-carboxamide CAS 2212021-82-2.

• Advanced Analytical Verification: Every batch is validated through HPLC, LC-MS, and Chiral HPLC to confirm chemical identity, molecular weight, and enantiomeric excess, ensuring the highest purity for downstream synthesis.

• Full Technical Documentation: We provide comprehensive support, including Certificate of Analysis (COA), MSDS, and Method of Analysis (MOA) for 5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-N-phenyl-1H-indole-2-carboxamide CAS 2212021-82-2.

• Scalable Production Capacity: Our China facility is equipped to support projects ranging from milligram-scale medicinal chemistry research to multi-kilogram industrial supply for Orforglipron production.

• Direct Source Advantage: As a primary manufacturer, we provide 5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-N-phenyl-1H-indole-2-carboxamide CAS 2212021-82-2 with efficient lead times and direct factory technical support.

Packaging & Storage

• Standard Packaging: 1kg/aluminum foil bag or 25kg/fiber drum with dual PE protection for chemical integrity.

• Storage Conditions: Store in a tightly closed container at -20°C or 2-8°C for optimal stability. Protected from light, heat, and moisture.

• Shelf Life: 24 months when stored under recommended conditions.

• Safety Handling: This material is a technical-grade chemical intended for industrial production and laboratory research use only. Avoid inhalation and direct contact.

Our logistics team ensures secure distribution of 5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-N-methyl-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-N-phenyl-1H-indole-2-carboxamide CAS 2212021-82-2 via global courier, air freight, and sea freight with temperature-controlled options available.

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