CAS 1784678-61-0 | Orforglipron intermediate Manufacturer & Supplier

Product Overview

5-Bromo-4-fluoro-1-methyl-1H-indazole (CAS 1784678-61-0) is a critical bicyclic heterocyclic building block used extensively in modern medicinal chemistry. As a key structural intermediate for the synthesis of Orforglipron, a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist, this compound plays a vital role in the development of advanced metabolic disease treatments. The precise positioning of the bromine and fluorine atoms on the indazole ring provides a unique electronic and steric profile, enabling complex cross-coupling reactions and molecular optimizations. As a leading manufacturer of 5-Bromo-4-fluoro-1-methyl-1H-indazole CAS 1784678-61-0 based in China, Conscientia Industrial utilizes high-precision organic synthesis and multi-stage purification protocols to ensure the highest structural integrity and chemical stability. Our production process is optimized to control regioisomeric purity, ensuring that the 1-methyl substitution is consistent across all batches. We maintain a strict purity profile to meet the rigorous technical requirements of global pharmaceutical R&D and large-scale API manufacturing.

Technical Specifications

• Product Name: 5-Bromo-4-fluoro-1-methyl-1H-indazole

• CAS Number: 1784678-61-0

• Category: Pharmaceutical Intermediates

• Quality Standard: In-House Specification

• Purity (HPLC): ≥98.0%

• Molecular Formula: C8H6BrFN2

• Molecular Weight: 229.05

• Loss on Drying: ≤1.0%

• Residue on Ignition: ≤0.1%

• Single Impurity: ≤1.0%

• Application: Orforglipron intermediate

• Brand: Conscientia Industrial

• Country of Origin: China

• Availability: In Stock

• Pricing: Competitive price based on order quantity

• Currency: USD

• Molecular Structure:

Why Partner with Conscientia Industrial

• Technical Quality Control: Our manufacturing process follows rigorous analytical protocols to ensure high-grade batch-to-batch consistency for 5-Bromo-4-fluoro-1-methyl-1H-indazole CAS 1784678-61-0.

• Advanced Analytical Verification: Every batch is validated through HPLC, GC, and Proton NMR to confirm chemical identity and minimize related substances or isomeric impurities.

• Full Technical Documentation: We provide comprehensive support, including Certificate of Analysis (COA), MSDS, and Method of Analysis (MOA) for 5-Bromo-4-fluoro-1-methyl-1H-indazole CAS 1784678-61-0.

• Scalable Production Capacity: Our China facility is equipped to support projects ranging from laboratory-scale research to multi-ton industrial supply, specifically for Orforglipron intermediate series.

• Direct Source Advantage: As a primary manufacturer, we provide 5-Bromo-4-fluoro-1-methyl-1H-indazole CAS 1784678-61-0 with efficient lead times and direct factory technical support.

Packaging & Storage

• Standard Packaging: 1kg/aluminum foil bag, 5kg/drum, or 25kg/fiber drum with dual PE protection for chemical integrity.

• Storage Conditions: Store in a tightly closed container in a cool, dry, and well-ventilated area. Keep away from strong oxidizing agents.

• Shelf Life: 24 months when stored under recommended conditions.

• Safety Handling: This material is a technical-grade chemical intended for industrial production and laboratory research use only. Wear appropriate protective equipment during handling.

Our logistics team ensures secure distribution of 5-Bromo-4-fluoro-1-methyl-1H-indazole CAS 1784678-61-0 via global courier, air freight, and sea freight.

Request a Quote & COA for 5-Bromo-4-fluoro-1-methyl-1H-indazole CAS 1784678-61-0 Today.