Product Overview
ShK-Dap22 (CAS 220384-25-8) is a potent and selective potassium channel blocker derived from the Stichodactyla helianthus neurotoxin (ShK), modified with a 2,3-diaminopropionic acid residue at position 22. In immunological and pharmacological research, this peptide is utilized to selectively target Kv1.3 voltage-gated potassium channels involved in T-lymphocyte activation and autoimmune disease models. Conscientia Industrial produces ShK-Dap22 using solid-phase peptide synthesis and HPLC purification to ensure strict sequence accuracy and high functional stability.
Technical Specifications
| Product Name: | ShK-Dap22 |
| Synonyms: | (Dap22)-Stichodactyla Helianthus Neurotoxin (ShK) |
| CAS Number: | 220384-25-8 |
| Category: | Peptides |
| Peptide Length: | 35 Amino Acids |
| One-letter Sequence: | RSCIDTIPKSRCTAFQCKHSM-Dap-YRLSFCRKTCGTC (Disulfide bridge: C3-C35; C12-C28; C17-C32) |
| Three-letter Sequence: | Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-Dap-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys (Disulfide bridge: Cys3-Cys35; Cys12-Cys28; Cys17-Cys32) |
| Molecular Formula: | C166H268N54O48S7 |
| Molecular Weight: | 4012.69 |
| Quality Standard: | In-House Specification |
| Appearance: | White to off-white lyophilized powder |
| Purity (HPLC): | ≥98.0% |
| Alternative Grade: | ≥95.0% |
| Water Content: | ≤10.0% |
| Acetate Salt Form: | Acetate Content ≤15.0% |
| Trifluoroacetate Salt Form: | TFA Content ≤15.0% |
| Manufacturer: | Conscientia Industrial |
| Brand: | Conscientia Industrial |
| Country of Origin: | China |
Why Choose Conscientia Industrial
- Quality Assurance: Every batch of ShK-Dap22 is verified by HPLC and mass spectrometry to ensure accurate disulfide linkage, high purity, and consistent lot-to-lot quality.
- Documentation: Certificate of Analysis (COA), Safety Data Sheet (SDS), and Method of Analysis (MOA) are provided to support regulatory compliance and technical requirements.
- Production Capacity: Synthesis infrastructure supports flexible orders from milligram research quantities to bulk batch manufacturing.
- Direct Supply: Direct factory supply ensures stable inventory, competitive pricing, and full technical support.
Packaging & Storage
- Packaging: Available in 1mg, 5mg, 10mg, 50mg, 100mg, 500mg, 1g, 10g in vials or in aluminium foil bags. Customized packaging and private labeling services are available upon request.
- Storage Condition: Store sealed at -20°C in a dry and dark place.
- Shelf Life: 24 months when properly stored under recommended conditions.
- Safety Handling: This product is intended for research and industrial use only. It is not intended for human or veterinary diagnostic or therapeutic use. Handle with proper personal protective equipment.
Shipping & Quotes
- Conscientia Industrial provides worldwide logistics solutions for ShK-Dap22 (CAS 220384-25-8), including international courier service, air freight, and sea freight. A complete set of shipping documents is provided to support international import and export requirements.
- Contact us today for the latest quotation, COA, SDS, and technical documentation.
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