Calciseptine CAS 178805-91-9

Product Overview

Calciseptine (CAS 178805-91-9) is a potent and highly selective polypeptide toxin originally isolated from the venom of the black mamba Dendroaspis polylepis. This natural peptide consists of 60 amino acids with four disulfide bridges and belongs to the three-finger toxin family. Within the Peptides and pharmacological research sectors, Calciseptine is recognized for its unique technical ability to act as a specific L-type calcium channel blocker. It effectively inhibits cardiac contractions and vascular smooth muscle relaxation by preventing calcium ion influx without affecting other ion channels or receptors. As a professitional manufacturer of Calciseptine CAS 178805-91-9 based in China, Conscientia Industrial utilizes precision solid-phase peptide synthesis and sophisticated folding protocols to recreate the natural disulfide connectivity. Our manufacturing process ensures that the secondary and tertiary structures of the peptide are perfectly preserved, which is critical for its biological activity in ion channel research and drug discovery. Our product maintains a strict purity profile to meet global technical requirements for electrophysiological studies, neurochemical analysis, and high-throughput screening applications.

Technical Specifications

• Product Name: Calciseptine
• CAS Number: 178805-91-9
• Sequence: Arg-Ile-Cys-Tyr-Ile-His-Lys-Ala-Ser-Leu-Pro-Arg-Ala-Thr-Lys-Thr-Cys-Val-Glu-Asn-Thr-Cys-Tyr-Lys-Met-Phe-Ile-Arg-Thr-Gln-Arg-Glu-Tyr-Ile-Ser-Glu-Arg-Gly-Cys-Gly-Cys-Pro-Thr-Ala-Met-Trp-Pro-Tyr-Gln-Thr-Glu-Cys-Cys-Lys-Gly-Asp-Arg-Cys-Asn-Lys (Disulfide bridge: Cys3-Cys22;Cys17-Cys39;Cys41-Cys52;Cys53-Cys58)
• Category: Peptides
• Quality Standard: In-House
• Purity (HPLC): ≥98.0%
• Molecular Formula: C299H468N90O87S10
• Molecular Weight: 7036.12
• Appearance: White or off-white lyophilized powder
• Peptide Content: ≥80%
• Solubility: Soluble in water
• Brand: Conscientia Industrial
• Country of Origin: China

Why Choose Conscientia Industrial

• Technical Quality Control: Our manufacturing process follows rigorous analytical protocols to ensure high-grade batch-to-batch consistency for Calciseptine CAS 178805-91-9.
• Advanced Analytical Verification: Every batch is validated through HPLC and Electrospray Ionization Mass Spectrometry (ESI-MS) to confirm chemical identity and ensure the correct mass and purity of the peptide sequence.
• Full Technical Documentation: We provide comprehensive support, including Certificate of Analysis (COA), MSDS, and Method of Analysis (MOA) specifically for Calciseptine CAS 178805-91-9.
• Scalable Production Capacity: Our China facility is equipped to support projects ranging from milligram-scale fundamental research to larger quantities for industrial pharmacological screening.
• Direct Source Advantage: As a primary manufacturer, we provide Calciseptine CAS 178805-91-9 with efficient lead times and direct factory technical support to assist with your specific research parameters.

Packaging & Storage

• Standard Packaging: 1mg, 10mg, 100mg, 1g, 10g lyophilized powder provided in high-purity glass vials or specialized tubes with secondary protective packaging.
• Storage Conditions: Store in a tightly closed container at -20°C or below for long-term stability. Protected from light and moisture.
• Shelf Life: 24 months from the date of manufacture when stored under recommended conditions.
• Safety Handling: This material is a technical-grade chemical intended for industrial production and laboratory research use only. It must be handled by trained professionals.

Our logistics team ensures secure distribution of Calciseptine CAS 178805-91-9 via global courier, air freight, and sea freight with temperature-controlled shipping options available upon request.

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